Set against the backdrop of the world's most dangerous hot spots, this thrilling romantic adventure stars Academy Award winner Angelina Jolie as Sarah Jordan, a sheltered American socialite living in London. When she meets Nick Callahan (Clive Owen) a renegade doctor, his commitment to humanitarian efforts in war-torn nations moves her deeply. Driven by her passion for Nick and his life's work, Sarah risks everything to embark on a perilous journey that leads to the volatile far corners of the earth.